Today is Lucrezia Borgia's birthday, born in Italy way back in 1480. Happy Birthday, Lucrezia!
Lucrezia has become notorious in history as a woman who will do anything for her family, including poisoning, sexual favors, and incest. The men of her family were worse in their actions, but it's Lucrezia who is the most notorious.*
Perhaps, if she were a man, Lucrezia would have been modestly infamous for being so ruthless and Machiavellian, but it seems to be even more outrageous that she did those things and was a female. Of course, if she were male, she wouldn't have had to resort to sneakier methods of getting her way such as using sex or a poison ring to guarantee the outcome she wanted; she would just have straight-out murdered the person in question, or perhaps gone ahead and led an army against them. But being a woman, she didn't have those methods at her disposal, so she used what she did have—her femininity and the misguided thought that women were the weaker sex, and wouldn't dare to act as she did.